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Phosphorylated insulin-like growth factor (IGF)-binding protein-1 (IGFBP-1) inhibits while non-phosphorylated IGFBP-1 stimulates IGF-I-induced amino acid uptake by cultured trophoblast cells

✍ Scribed by J. Yu; M. Iwashita; Y. Kudo; Y. Takeda


Book ID
117735265
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
850 KB
Volume
8
Category
Article
ISSN
1096-6374

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Osteogenic protein-1 (OP-1 or BMP-7) stimulates new bone formation in vivo and induces cell proliferation and differentiation of osteoblasts in vitro. Previous studies from our laboratory revealed that OP-1 led to a two-to threefold increase in steady-state insulin-like growth factor-I (IGF-I) and I