Understanding the transition states of p
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Adam G. Cassano; Vernon E. Anderson; Michael E. Harris
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Article
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2003
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Wiley (John Wiley & Sons)
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English
โ 175 KB
๐ 2 views
## Abstract The nucleotides of DNA and RNA are joined by phosphodiester linkages whose synthesis and hydrolysis are catalyzed by numerous essential enzymes. Two prominent mechanisms have been proposed for RNA and protein enzyme catalyzed cleavage of phosphodiester bonds in RNA: (a) __intra__molecul