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Phosphorus Pentoxide in Organic Synthesis, XVIII. Phosphorus Pentoxide and Secondary Amine Mixtures in a New Synthesis ofN6,N6-Dialkyl- andN6-Alkyl,N6-aryl-9H-purin-6-amines

✍ Scribed by El-Bayouki, Khairy A. M. ;Nielsen, Flemming E. ;Pedersen, Erik B.


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
263 KB
Volume
1985
Category
Article
ISSN
0947-3440

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✦ Synopsis


Abstract

A series of N^6^,N^6^‐disubstituted 9__H__‐purin‐6‐amines 2ai was prepared from 5‐acetamido‐6‐amino‐2‐methylpyrimidin‐4(3__H__)‐one (1) and a secondary amine or its hydrochloride in the presence of phosphorus pentoxide and triethylamine hydrochloride.