Treatment of esters with diisobutylaluminum hydride (DIBAL) in the presence of lithio-trialkylphosphonoacetate results in improved yields of the homologated a,B-unsaturated esters. The problematic overreduction, which has previously observed in the half reduction of esters using DIBAL, is minimal (~
✦ LIBER ✦
Phosphonium-Supported Triphenylphosphine Reagent: An Improved Access to α-Fluoro α,β-Unsaturated Esters.
✍ Scribed by Ludivine Zoute; Celine Lacombe; Jean-Charles Quirion; Andre B. Charette; Philippe Jubault
- Book ID
- 102001011
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 23 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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