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Phospholipid-Sensitive Ca2+-Dependent Protein Kinase Preferentially Phosphorylates Serine-115 of Bovine Myelin Basic Protein

โœ Scribed by R. Scott Turner; C.-H. Jen Chou; Gonzalo J. Mazzei; Philip Dembure; J. F. Kuo


Book ID
111172836
Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
802 KB
Volume
43
Category
Article
ISSN
0022-3042

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Gangliosides inhibit the phosphorylation of both small and large rat myelin basic proteins (SMBP, LMBP) by an endogenous phospholipid-sensitive Ca\*+-dependent protein kinase (C-kinase). Using a rat brain myelin preparation in an in vitro phosphorylation assay system, we determined the inhibition co