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Phospholipases A2 in the reproductive system of the bull

✍ Scribed by Seppo Rönkkö; Risto Lahtinen; Tapani Vanha-Perttula


Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
981 KB
Volume
23
Category
Article
ISSN
0020-711X

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Molecular modeling in the design of phos
✍ William C. Ripka; William J. Sipio; William G. Galbraith 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 393 KB

The X-ray structures of pancreatic bovine and porcine phospholipases A2 have been used along with interactive computer graphics to design conformationally rigid, novel compounds (1-meta-hydroxybenzyl-2-substituted acenaphthenes) directed at the active sites of these enzymes. In vitro testing confirm