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Phospholipases A2 and Inflammatory Responses in the Central Nervous System

โœ Scribed by Grace Y. Sun; Phullara B. Shelat; Michael B. Jensen; Yan He; Albert Y. Sun; Agnes Simonyi


Book ID
107568638
Publisher
Humana Press Inc
Year
2009
Tongue
English
Weight
448 KB
Volume
12
Category
Article
ISSN
1535-1084

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Extracellular phospholipase A2 inhibitor
โœ Florence Pinto; Talma Brenner; Phyllis Dan; Miron Krimsky; Saul Yedgar ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 127 KB

Phospholipase A2 (PLA2) plays a key role in the production of proinflammatory mediators, namely the arachidonic acid-derived eicosanoids, lysophospholipids, and platelet-activating factor, and indirectly influences the generation of cytokines, nitric oxide (NO), and free radicals. Accordingly, regul