Extracellular phospholipase A2 inhibitor
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Florence Pinto; Talma Brenner; Phyllis Dan; Miron Krimsky; Saul Yedgar
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Article
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2003
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John Wiley and Sons
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English
โ 127 KB
Phospholipase A2 (PLA2) plays a key role in the production of proinflammatory mediators, namely the arachidonic acid-derived eicosanoids, lysophospholipids, and platelet-activating factor, and indirectly influences the generation of cytokines, nitric oxide (NO), and free radicals. Accordingly, regul