Reduced expression of phospholipase c-δ,
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Naoki Yoshimi; Aijin Wang; Hiroki Makita; Masumi Suzui; Hideki Mori; Yukio Okano
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Article
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1994
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John Wiley and Sons
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English
⚖ 694 KB
## Abstract Phospholipase C (PLC), Which hydrolyzes phosphoinositides, has been implicated as a key enzyme in signal transduction. We examined the expression of an isozyme of PLC, PLC,‐δ, in rat colon neoplasms induced by methylazoxymethanol (MAM) acetate. Large‐bowel neoplasms were observed in fiv