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Phospholipase A2(PLA2) activity in undifferentiated U937 cells

✍ Scribed by W. Galbraith; K. A. Paschetto; T. M. Stevens; J. S. Kerr

Publisher
SP Birkhäuser Verlag Basel
Year
1989
Tongue
English
Weight
210 KB
Volume
27
Category
Article
ISSN
1420-908X

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The human undifferentiated histiocytic cell-line U937 can be induced to differentiate by incubation with 12-0-tetradecanoylphorbol-13-acetate (TPA) into macrophagelike cells. Dexamethasone reduced the prostaglandin production in TPA-differentiated U937 cells dose dependently, whereas undifferentiate