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Phospholipase A2activation as a therapeutic approach for cognitive enhancement in early-stage Alzheimer disease

✍ Scribed by Evelin L. Schaeffer; Orestes V. Forlenza; Wagner F. Gattaz

Book ID: 105882557
Publisher: Springer
Year: 2008
Tongue: English
Weight: 308 KB
Volume: 202
Category: Article
ISSN: 0033-3158
DOI: 10.1007/s00213-008-1351-0

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## Abstract Alzheimer's disease (AD) is the most common form of dementia and is pathologically characterized by senile plaques, neurofibrillary tangles, synaptic disruption and loss, and progressive neuronal deficits. The exact mechanism(s) of AD pathogenesis largely remain unknown. With advances i