Phospholipase A2 mechanism: Inhibition and role in arachidonic acid release
β Scribed by Edward A. Dennis
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 919 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0272-4391
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The lipid mediators generated by phospholipases A(2) (PLA(2)), free arachidonic acid (AA), eicosanoids, and platelet-activating factor, modulate neuronal activity; when overproduced, some of them become potent neurotoxins. We have shown, using primary cortical neuron cultures, that glutamate and sec
## Abstract The thioredoxin (Trx) system, comprising Trx, the selenoprotein thioredoxin reductase (TrxR), and NADPH, functions as an antioxidant system. Trx has various biological activities including growth control and antiβapoptotic properties, and the Trx system offers a target for the developme
The stimulation of cultured guinea pig alveolar macrophages by the chemotactic peptide N-formyl-L-methionyl-L-leucyl-L-phenylalanine, or by the phospholipid inflammatory mediator platelet activating factor (PAF) induced an increase in arachidonic acid release and its cyclooxygenase products. This re