Inhibition of phosphoinositide 3-kinase
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Ezra Aksoy; Wim Vanden Berghe; Sophie Detienne; Zoulikha Amraoui; KathrineβA. Fi
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Article
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2005
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John Wiley and Sons
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English
β 338 KB
Phosphoinositide 3-kinases (PI3K) are known to regulate Toll-like receptor (TLR)-mediated inflammatory responses, but their impact on the different pathways of TLR signaling remains to be clarified. Here, we investigated the consequences of pharmacological inhibition of PI3K on Toll-IL-1 receptor do