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Phosphoinositide 3-kinase induced activation and cytoskeletal translocation of protein kinase CK2 in protease activated receptor 1-stimulated platelets

✍ Scribed by Kyoichi Nakanishi; Hidemi Toyoda; Sigeki Tanaka; Hatsumi Yamamoto; Yoshihiro Komada; Esteban C. Gabazza; Tatsuya Hayashi; Koji Suzuki; Masaru Ido

Book ID
116914559
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
706 KB
Volume
126
Category
Article
ISSN
0049-3848

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## Abstract The effects of P2Y2 purinoceptor activation on c‐Fos expression and the signaling pathways evoked by extracellular ATP/UTP in HeLa cells were investigated. We found that P2Y2 activation induced c‐Fos protein and phosphorylated the extracellular signal‐regulated kinases 1 and 2 (ERK1/2).