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Phosphoinositide 3-Kinase-Dependent Antagonism in Mammalian Olfactory Receptor Neurons

✍ Scribed by Ukhanov, K.; Brunert, D.; Corey, E. A.; Ache, B. W.


Book ID
118277964
Publisher
Society for Neuroscience
Year
2011
Tongue
English
Weight
451 KB
Volume
31
Category
Article
ISSN
0270-6474

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## Abstract Many G protein coupled receptors (GPCRs) cause phosphorylation of MAP kinases through transactivation of the epidermal growth factor receptor (EGF‐R), leading to increased cell survival and growth, motility, and migration. Phosphoinositide 3‐kinase (PI3K) is one of the important cell su