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Phosphoinositide 3-kinase, but not mitogen-activated protein kinase, pathway is involved in hepatocyte growth factor-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes

✍ Scribed by Cynthia R.L. Webster; M.Sawkat Anwer


Book ID
111721443
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
342 KB
Volume
33
Category
Article
ISSN
0270-9139

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The role of diacylglycerol (DAG) in hormonal induction of S phase was investigated in primary cultures of rat hepatocytes. In this model, several agonists that bind to G protein-coupled receptors act as comitogens when added to the cells soon after plating (i.e., in Go/early Gl phase), while the cel