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Phosphoglucose isomerase (PGI) variants in the Netherlands

✍ Scribed by S. G. Welch; H. A. Bartstra; R. A. Geerdink

Book ID
104753736
Publisher
Springer
Year
1977
Tongue
English
Weight
150 KB
Volume
37
Category
Article
ISSN
0340-6717

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✦ Synopsis

Six hundred individuals of pure Dutch ancestry have been typed for their erythrocyte phosphoglucose isomerase phenotypes by starch gel and cellulose acetate electrophoresis. In two individuals a variant phenotype was discovered. One phenotype was found to be indistinguishable from PGI-Phillips. The other variant would appear to be a new phenotype and has been designated PGI-Jager.

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Phosphoglucose isomerase (PGI) and 16 other biochemical genetic markers were studied in an Israeli-Arab family previously described for hereditary deficiency of adenylate kinase (AK) and glucose 6-phosphate dehydrogenase (G6PD). In this inbred family a rare PGI\*3 allele was observed in 11 of 32 mem