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Phosphodiesterase-linked inhibition of nonmicturition activity in the isolated bladder

✍ Scribed by J.I. Gillespie

Book ID
109051186
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
289 KB
Volume
93
Category
Article
ISSN
1464-4096

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The inhibition by xanthine phosphodieste
The inhibition by xanthine phosphodiesterase inhibitors of the induction of alkaline phosphatase activity in HeLa cells: Relationship of enzyme activity to cyclic AMP concentrations
✍ Walker Wharton; Barry Goz πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 English βš– 681 KB

## Abstract The three xanthine derivatives, caffeine, theophylline and 3‐isobutyl‐1‐methyl‐xanthine (IBMX) produced dose‐dependent increases in cyclic AMP concentrations in HeLa cells after long term treatment. Only IBMX produced increases over the first 60 minutes, with a peak of approximately 5‐f