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Phosphodiesterase-Inhibiting Glycosides from Symplocos racemosa

✍ Scribed by Viqar Uddin Ahmad; Muhammad Athar Abbasi; Muhammad Zubair; Naheed Fatima; Umar Farooq; M. Iqbal Choudhary

Book ID
102257190
Publisher
John Wiley and Sons
Year
2004
Tongue
German
Weight
98 KB
Volume
87
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Phytochemical investigation of Symplocos racemosa resulted in the isolation of two new glycosides, symploracemoside (1) and symplomoside (2), which are structurally related to the reported benzoylsalireposide (3) and salireposide (4). The structure elucidation of the isolated compounds was based primarily on 1D‐ and 2D‐NMR analysis, including COSY, NOESY, HMQC, and HMBC correlations. These glycosides showed inhibitory activity against snake‐venom phosphodiesterase I.

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