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Phosphodiesterase 4D and 5-lipoxygenase activating protein genes and risk of ischemic stroke in Sardinians

✍ Scribed by Quarta, Giovanni; Stanzione, Rosita; Evangelista, Anna; Zanda, Bastianina; Di Angelantonio, Emanuele; Marchitti, Simona; Di Castro, Sara; Di Vavo, Marta; Volpe, Massimo; Rubattu, Speranza

Book ID
109849167
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
134 KB
Volume
17
Category
Article
ISSN
1018-4813

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## Abstract ## Objective To explore the modulation of 5‐lipoxygenase–activating protein (FLAP) and 5‐lipoxygenase (5‐LOX) expression in human osteoarthritic (OA) chondrocytes, their relative implications in leukotriene B~4~ (LTB~4~) production, the effect of different factors on this system, and t