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Phosphodiesterase 11 (PDE11) regulation of spermatozoa physiology

✍ Scribed by Wayman, C; Phillips, S; Lunny, C; Webb, T; Fawcett, L; Baxendale, R; Burgess, G


Book ID
110042417
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
255 KB
Volume
17
Category
Article
ISSN
0955-9930

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Phosphodiesterases (PDEs) are critically involved in the determination of intracellular cyclic nucleotide levels. PDEs are heterodimers containing a conserved C-terminal catalytic domain and an N-terminal regulatory domain. Within their regulatory domain, 5 PDE families contain GAF domains, which ar