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Phosphodiester Substrates for Incorporation of Nucleotides in DNA Using HIV-1 Reverse Transcriptase

✍ Scribed by Anne Giraut; Natalia Dyubankova; Xiao-ping Song; Piet Herdewijn

Book ID
101820728
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
309 KB
Volume
10
Category
Article
ISSN
1439-4227

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## Background: To gain a molecular understanding of a biochemical process, the crystal structure of enzymes that catalyze the reactions involved is extremely helpful. often the question arises whether conformations obtained in this way appropriately reflect the reactivity of enzymes, however. rates