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Phosphoantigens and aminobisphosphonates: New leads targeting γδ T lymphocytes for cancer immunotherapy

✍ Scribed by Christian Belmant; Donatella Decise; Jean-Jacques Fournié


Book ID
119226009
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
303 KB
Volume
3
Category
Article
ISSN
1740-6773

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## Abstract T lymphocytes are classified into 2 subsets based on their T‐cell receptor (TCR) expression. The vast majority of T cells expresses an αβ TCR heterodimer. These αβ T cells recognize antigenic peptides presented by MHC class I (for CD8^+^ T cells) or MHC class II molecules (for CD4^+^ T