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Phosphinic Acid Induced Reversal of Regioselectivity in Pd-Catalyzed Hydrophosphinylation of Alkynes with Ph2P(O)H

✍ Scribed by Li-Biao Han; Ruimao Hua; Masato Tanaka


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
109 KB
Volume
37
Category
Article
ISSN
0044-8249

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The prolonged photo-Arbuzov reaction (3 weeks, Hg lamp) of 1,3,5-trichloro-benzene with a large excess of trimethyl phosphite (as a solvent) at 508 gives moderate yields of dimethyl (3,5-dichlorophenyl)phosphonate (1; 14.5%), tetramethyl (5-chloro-1,3-phenylene)bis[phosphonate] (2; 35.4%), and hexam