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Phosphine-free palladium-catalysed direct C2-arylation of benzothiophenes with aryl bromides

โœ Scribed by Zhao, Liqin; Bruneau, Christian; Doucet, Henri


Book ID
120464581
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
655 KB
Volume
69
Category
Article
ISSN
0040-4020

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## Abstract Heteroaromatics bearing unprotected hydroxyalkyl functions can be arylated using aryl or heteroaryl bromides, __via__ palladiumโ€catalysed carbonโ€hydrogen bond activation/arylation. Good yields were generally obtained using 0.01โ€“0.5โ€…mol% of the airโ€stable palladium acetate complex as the