Phosphide-borane complexes as key intermediates in the synthesis of optically active 1,3-oxaphospholanes
✍ Scribed by Pascal Pellon; Céline Le Goaster; Gilles Marchand; Beatrice Martin; Loic Toupet
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 248 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1042-7163
No coin nor oath required. For personal study only.
✦ Synopsis
The syntheses, from the triphenylphosphine-borane complex, of chiral 1,3-oxaphospholanes and optically active bis-1,3-oxaphospholanes, obtained by cleavage of a carbon-phosphorus bond with lithium, are described.
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The reaction of propargyl alcohol derivatives with the complex [Cp\*RuCl(dippe)] [dippe = 1,2-bis(diisopropylphosphane)ethane] and NaBPh 4 in MeOH yields hydrido(3-hydroxyalkynyl) compounds [Cp\*Ru(H){CϵCC(OH)RRЈ}-(dippe)][BPh 4 ] [R, RЈ = Ph, Ph (1a); H, Ph (1b); H, Me (1c)]. These represent interm