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Phosphatidylinositol 4,5-bisphosphate: Targeted production and signaling

✍ Scribed by Sun, Yue; Thapa, Narendra; Hedman, Andrew C.; Anderson, Richard A.

Book ID
125421901
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
609 KB
Volume
35
Category
Article
ISSN
0265-9247

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## Abstract The protein kinase AKT1 (v‐akt murine thymoma viral oncogene homolog 1), also referred to as protein kinase B (PKB), is an essential mediator of the phosphatidylinositol 3‐kinase signaling pathway. Elevated activity of AKT1 is common in human cancer. Localization at the plasma membrane,