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Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes

✍ Scribed by Janet Glassford; Elena Vigorito; Inês Soeiro; Patricia A. Madureira; Georgia Zoumpoulidou; Jan J. Brosens; Martin Turner; Eric W.-F. Lam


Book ID
102823514
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
552 KB
Volume
35
Category
Article
ISSN
0014-2980

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## Abstract The rapid, non‐genomic actions of 1,25‐dihydroxyvitamin D~3~ [1,25(OH)~2~D~3~] have been well described, however, the role of the nuclear vitamin D receptor (VDR) in this pathway remains unclear. To address this question, we used VDR(+/+) and VDR(−/−) osteoblasts isolated from wild‐type