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Phosphatidylinositol-3-kinase activation and atypical protein kinase C ζ phosphorylation characterize the DMSO signalling in erythroleukemia cells

✍ Scribed by Amelia Cataldi; Roberta Di Pietro; Lucia Centurione; Alfredo Grilli; Giuseppina Cutroneo; Sebastiano Miscia


Book ID
114283498
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
378 KB
Volume
12
Category
Article
ISSN
0898-6568

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Protein kinase C ζ nuclear translocation
✍ A. Cataldi; L. Centurione; R. Di Pietro; M. Rapino; D. Bosco; G. Grifone; F. Gar 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 334 KB

## Abstract Friend erythroleukemia cells require high doses (15 Gy) of ionizing radiation to display a reduced rate of proliferation and an increased number of dead cells. Since ionizing radiation can activate several signaling pathways at the plasma membrane which can lead to the nuclear transloca