✦ LIBER ✦

Phosphatidyl glycerol — a major component of pulmonary surfactant

✍ Scribed by Raymond C. Pfleger; Rogene F. Henderson; James Waide

Publisher: Elsevier Science
Year: 1972
Tongue: English
Weight: 805 KB
Volume: 9
Category: Article
ISSN: 0009-3084
DOI: 10.1016/0009-3084(72)90033-3

No coin nor oath required. For personal study only.

✦ Synopsis

Phosphatidyl glycerol has been isolated and characterized from the pulmonary surfactant lipids of Beagle dogs. The techniques included: (a) Isolation of individual phospholipids by preparative thin-layer chromatography (TLC); (b) Acidic, basic and two-dimensional TLC of intact phospholipids; (c) Identification of certain functional groups by color reactions; (d) Enzymatic and methanolic-alkaline hydrolysis of intact phosphatides; (e) TLC separation and identification of hydrolyzate products; (f) Quantitative chemical analyses of glycerol and phosphorus; (g) TLC of derivatives of both lipids and polar headgroups; and (h) Infrared spectral analysis of glycerylphosphorylglycerol and other glycerylphosphorylesters.

Phosphatidyl glycerol accounts for 10 ~ of the surfactant phospholipid phosphorus and was at least as surface active as surfactant lecithin.

📜 SIMILAR VOLUMES

Surface respreading after collapse of mo

Surface respreading after collapse of monolayers containing major lipids of pulmonary surfactant

✍ Blair D. Fleming; Kevin M.W. Keough 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 397 KB

Isotherms have been obtained near 37°C for a series of repetitive compressions and expansions of monolayers that contain major components of lung suffactant. The minimum surface tension or maximum surface pressure which could be achieved under conditions of dynamic compression, and the rate of retur

A sulfate ester of phosphatidyl glycerol

A sulfate ester of phosphatidyl glycerol (diether analogue) from Halobacterium cutirubrum

✍ A.J. Hancock; M. Kates 📂 Article 📅 1972 🏛 Elsevier Science 🌐 English ⚖ 203 KB

The major polar lipids identified in Halobacterium cutirubrum and other extreme halophiles are the diphytanyl ether analogues of phosphatidyl glycerophosphate and phosphatidyl glycerol, and a glycolipid sulfate esterl,e). A minor unidentified polar component, labelled both with 3Zp and 3sS, has also

Depletion of pulmonary surfactant — CoMP

Depletion of pulmonary surfactant — CoMP interaction with phospholipase A2

✍ Ramesh Chandra; H.G. Raj; Sujata Wangkheimayum; Mukta Dhawan; Rajni Malhotra 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 60 KB

Pulmonary disease is a component of dist

Pulmonary disease is a component of distal arthrogryposis type 5

✍ Marc S. Williams; C. Gregory Elliott; Michael J. Bamshad 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 244 KB 👁 1 views

Proline hydroxylation alters the electro

Proline hydroxylation alters the electrophoretic mobility of pulmonary surfactant-associated protein A

✍ David S. Phelps; Joanna Floros 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB

A Theoretical Model of Pulmonary Surfact

A Theoretical Model of Pulmonary Surfactant Multilayer Collapse under Oscillating Area Conditions

✍ Melissa A. Krueger; Donald P. Gaver III 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 176 KB

Monolayers of adsorbed pulmonary surfactant collapse under compression and respread to the interface when the area expands. These mechanisms contribute to the large area hysteresis seen experimentally in a pulsating bubble surfactometer. This paper presents an analytical model which adds monolayer c