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Phosphatidic acid activation of protein kinase C in LA-N-1 neuroblastoma cells

✍ Scribed by Dominique Lang; Anant N. Malviya; Alphonse Hubsch; Julian N. Kanfer; Louis Freysz

Book ID
116125227
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
393 KB
Volume
201
Category
Article
ISSN
0304-3940

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Acrylonitrile (ACN) is classified by IARC as a probable carcinogen. Chronic exposure to ACN increases the incidence of tumors in various organs of test animals, including the brain and lung. ERK1/2 activation plays crucial roles in cell proliferation and is involved in many steps of tumor progressio