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Phosphated crosslinked guar for colon-specific drug delivery: II. In vitro and in vivo evaluation in the rat

✍ Scribed by Irit Gliko-Kabir; Boris Yagen; Muhammad Baluom; Abraham Rubinstein


Book ID
114163866
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
156 KB
Volume
63
Category
Article
ISSN
0168-3659

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In vitro and in vivo evaluation of a nov
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The aim of this study was to estimate colon-specific drug delivery of a novel capsule (CS capsule). Theophylline was used as model drug and little was released from the CS capsules in the release medium mimicking physiological environment of stomach to small intestine. However, 66.7 +/- 8.8% theophy