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Phorbol esters induce immediate-early genes and activate cardiac gene transcription in neonatal rat myocardial cells

โœ Scribed by Preston M. Dunnmon; Kazumi Iwaki; Scott A. Henderson; Anjan Sen; Kenneth R. Chien


Book ID
115981238
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
862 KB
Volume
22
Category
Article
ISSN
0022-2828

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## Abstract Human T cells require two discrete signals to initiate their proliferation. In Jurkat T cells the first signal can be provided by the phorbol ester TPA and the second by the calcium ionophore A23187. We have isolated a cDNA from Jurkat T cells representing mRNA induced by TPA but inhibi