Phorbol esters can persistently replace
โ
Toshikazu Takeshita; Yuso Goto; Masataka Nakamura; Masahiro Fujii; Masafumi Iwam
๐
Article
๐
1988
๐
John Wiley and Sons
๐
English
โ 799 KB
A selected clone from an IL-2-dependent human T-cell line was persistently propagated in the presence of phorbol esters with the ability to activate protein kinase C (PKC), such as 12-0-tetradecanoylphorbol-I 3-acetate (TPA) or phorbol-12,1.3-dibutylate (PDBu). Thus, a TPA(PD6u)-dependent T-cell lin