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Phorbol ester TPA up regulates human platelets α2-adrenoceptors in vitro

✍ Scribed by X.-L. Wang; J. Gong; O.-E. Brodde


Book ID
115885026
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
223 KB
Volume
183
Category
Article
ISSN
0014-2999

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✍ Maurizio Cutolo; Giuseppe Carruba; Barbara Villaggio; Domenico A. Coviello; Jean 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 307 KB

## Abstract In the present work, we have inspected expression of estrogen receptors (ER) and their regulation by the phorbol diester 12‐O‐tetradecanoylphorbol 13‐acetate (TPA) in a leukemic cell line, the THP‐1 cells, using multiple experimental approaches. Firstly, ligand binding assay (LBA) revea