𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains

✍ Scribed by Naka, Michiko; Nishikawa, Masakatsu; Adelstein, Robert S.; Hidaka, Hiroyoshi


Book ID
109732862
Publisher
Nature Publishing Group
Year
1983
Tongue
English
Weight
376 KB
Volume
306
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Enhancement of phorbol ester-induced pro
✍ James C. Gay; Ella S. Stitt πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 962 KB

We have shown that platelet-activating factor (PAF), a weak primary stimulus for neutrophil superoxide generation, synergistically enhances neutrophil oxidative responses to the tumor promoter phorbol myristate acetate (PMA). Since PMA is known to cause cytosol-to-membrane shift of calcium-activated

Bile acids, non-phorbol-ester-type tumor
✍ X. P. Huang; X. T. Fan; J. F. Desjeux; M. Castagna πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 French βš– 846 KB

Protein kinase C (PKC) is the target for a number of tumor promoters. The mechanism underlying the promoting effects of bile acids in colorectal cancer is not understood. We report that sodium deoxycholate (DOC) triggered activation of PKC in physiological conditions. The biphasic effects of DOC upo

Protein kinase C activation and down-reg
✍ Jari E. HeikkilΓ€; GΓΆran Γ…kerlind; Karl E. O. Γ…kerman πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 933 KB

The role of protein kinase C activation in changes in muscarinic receptor functions and in the appearance of biochemical properties characteristic of neuronal cells was studied in SH-SY5Y human neuroblastoma cells induced to differentiate with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (

Enhancement of Ca2+channel currents in h
✍ Helen L. Reeve; Peter F. T. Vaughan; Chris Peers πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 985 KB

The effects of phorbol esters on Ca 2 + channel currents in human neuroblastoma SH-SY5Y cells were studied using whole-cell patch-clamp recordings. Bath application of 12-O-tetradecanoylphorbol-13-acetate (TPA) or phorbol 12, 13-dibutyrate (PDBu; 100 nM to 1 #M), known activators of protein kinase C