Phorbol ester enhances both interleukin 2 receptor expression and immunoglobulin secretion in human Epstein-Barr virus-immortalized B cells

Enhanced expression of human T-cell leuk

Enhanced expression of human T-cell leukemia/lymphoma virus in neoplastic T cells induced to proliferate by phorbol ester and interleukin-2

✍ Florry A. Vyth-Dreese; Jan E. De Vries 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 French ⚖ 847 KB

## Abstract Peripheral blood T cells from a patient with T‐cell chronic lymphocytic leukemia (T‐CLL) failed to respond to mitogenic lectins or alloantigens but could be induced to proliferate by the addition of exogenous interleukin‐2 (IL‐2). The T‐CLL cells also proliferated in response to 12‐__O_