Mesna does not reduce cisplatin induced
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Barbara C. Millar; Zahid H. Siddik; John L. Millar; Sally Jinks
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Article
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1985
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Springer
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English
โ 235 KB
Although mesna afforded protection against the cytotoxicity of cisplatin in Chinese hamster cells, line V-79-753B, in vitro, there was no evidence for protection against nephrotoxicity when this drug combination was examined in the rat. It seems likely that cisplatin-induced nephrotoxicity is mediat