PHEX expression in parathyroid gland and parathyroid hormone dysregulation in X-linked hypophosphatemia
β Scribed by Tom D. Blydt-Hansen; Harriet S. Tenenhouse; Paul Goodyer
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 50 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0931-041X
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## Abstract We have previously reported that parathyroid hormone (PTH) and PTH related protein (PTHrP) stimulate expression of interleukinβ6 (ILβ6) and leukemia inhibitory factor (LIF) in osteoblasts in vitro. In the current study, we have developed a model of hormone injection into the subcutaneou
Intermittent administration of parathyroid hormone (PTH) activates new sites of bone formation by stimulating osteoblast differentiation and function resulting in an increase in bone mass. Because integrins have been shown to play a crucial role in osteoblast differentiation and bone formation, in t