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Phenytoin-induced glutathione depletion in rat peripheral nerve

✍ Scribed by Ángel Raya; Juan Gallego; Francisco Bosch-Morell; Joaquin Romá; Francisco J. Romero

Book ID
113386679
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
265 KB
Volume
19
Category
Article
ISSN
0891-5849

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📜 SIMILAR VOLUMES

Halothane hepatotoxicity in glutathione
Halothane hepatotoxicity in glutathione depleted rats
✍ Klaus-Peter Wilhelm; Maged Younes; Dieter Sellin; Claus-Peter Siegers 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 610 KB

Experimental models for halothane hepatotoxicity require microsomal enzyme induction by phenobarbital or triiodo-thyronine pretreatment and hypoxic conditions. The role of GSH in the metabolism of halothane, however, is still unclear. We therefore pretreated male rats with phorone to deplete hepatic