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Phenytoin II: In vitro–in vivo bioequivalence standard for 100-mg phenytoin sodium capsules

✍ Scribed by Vinod P. Shah; Vadlamani K. Prasad; Corinne Freeman; Jerome P. Skelly; Bernard E. Cabana


Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
287 KB
Volume
72
Category
Article
ISSN
0022-3549

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Phenytoin I: In vitro–in vivo correlatio
✍ Vinod P. Shah; Vadlamani K. Prasad; Treva Alston; Bernard E. Cabana; Richard P. 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 313 KB

Compound IV was prepared in the same manner as described for 111, but with piperazinefi. After evaporation of the solvents, the residue crystallized from 1:l diethyl ether-petroleum ether: 2.3 g, 32% yield, mp 120- 122'; NMR (chloroform-d): d 2.65 (s, 16H, CHz), 3.87 (s, 18H, OCHB),