Phenylthio(Phs) migration in the stereocontrolled synthesis of allylic alcohols with 1, 4 related chiral centres.

✍ Scribed by Varinder K. Aggarwal; Stuart Warren

• Publisher: Elsevier Science
• Year: 1986
• Tongue: French
• Weight: 214 KB
• Volume: 27
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)83952-0

✦ Synopsis

Stereoselective aldol products are transformed by PhS migration into lactones, tetrahydrofurans, and, by subsequent Evans-Mislow rearrangement, into the title compounds with complete stereochemical control.