Phenylselenoacetaldehyde, a Useful Reagent for the Homologative Conversion of Halides to Phenylselenomethyl Ketones

✍ Scribed by Roger Baudat; Martin Petrzilka

• Publisher: John Wiley and Sons
• Year: 1979
• Tongue: German
• Weight: 310 KB
• Volume: 62
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.19790620505

✦ Synopsis

Abstract

The conversion of primary, secondary and vinylic halides to the two C‐atoms homologated phenylselenomethyl ketones 8 is described. The method involves addition of the readily available phenylselenoacetaldehyde 5 to the Grignard reagents 9 and oxidation of the resulting β‐hydroxy‐selenides 10 (Scheme 3).