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PHENYLETHYLMALONIC METHYL ESTER. A NEW METHOD OF SYNTHESIS

โœ Scribed by Rising, Mary M.; Zee, Tsoh-Wu


Book ID
127123589
Publisher
American Chemical Society
Year
1928
Tongue
English
Weight
415 KB
Volume
50
Category
Article
ISSN
0002-7863

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Convergent synthesis of leukotriene a me
โœ John G. Gleason; D.Boles Bryan; Charles M. Kinzig ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 172 KB

A convergent total synthesis of methyl 5,6-oxido-7,9,11,14-eicosapentaenoate from act-2-yn-l-01 and methyl I-formylbutyrate is described. Leukotriene A (1) has been proposed by Samuelsson and his co-workers to be a shortlived intermediate in the arachidonic acid cascade in human and rabbit leukocyte