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Phenylethyl Glycosides from Digitalis lanata

✍ Scribed by Hasan Kırmızıbekmez; Engin Celep; Milena Masullo; Carla Bassarello; Erdem Yeşilada; Sonia Piacente


Publisher
John Wiley and Sons
Year
2009
Tongue
German
Weight
178 KB
Volume
92
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Three new phenylethyl glycosides, 3′′′′‐__O‐__methylmaxoside (=2‐(3,4‐dihydroxyphenyl)ethyl Oβ‐D‐glucopyranosyl‐(1→3)‐O‐[β‐D‐glucopyranosyl‐(1→6)]‐4‐O‐(E)‐feruloyl‐β‐D‐glucopyranoside; 1), digilanatosides A (=2‐(3,4‐dihydroxyphenyl)ethyl O‐6‐O‐(E)‐sinapoyl‐β‐D‐glucopyranosyl‐(1→3)‐4‐O‐(E)‐caffeoyl‐β‐D‐glucopyranoside; 2), and digilanatoside B (=2‐(3,4‐dihydroxyphenyl)ethyl O‐6‐O‐(E)‐p‐coumaroyl‐β‐D‐glucopyranosyl‐(1→3)‐4‐O‐(E)‐caffeoyl‐β‐D‐glucopyranoside; 3) were isolated from the aerial parts of Digitalis lanata, along with two known phenylethyl glycosides, purpureaside A and maxoside, a phenylpropanoid glucose ester, 1‐O‐(E)‐feruloyl‐β‐glucopyranose, a benzoquinolethanoid glucoside, cornoside, a cardenolide, lanatoside C, a furostane‐type steroidal saponin, purpureagitoside, and a disaccharide, sucrose. Their structures were elucidated on the basis of spectroscopic evidence (1D‐ and 2D‐NMR, and HR‐MALDI‐MS).


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