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Phenylalanine, other large neutral amino acids and RNA catabolites as markers for protein biosynthesis in phenylketonuria

✍ Scribed by Peter C. Clemens; Jens Gunter Burmester; Gert Wiegand; Bernhard H. Prankel; Editha Halfmann; Norbert Erb; Jürgen Müller-Wickop

Book ID
116030802
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
214 KB
Volume
42
Category
Article
ISSN
1532-8600

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✍ L. Dillehay; R. Bass; E. Englesberg 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 872 KB

## Abstract Phenylalanine in high concentrations inhibits the growth of mouse A9 cells. Protein synthesis is inhibited earlier and more severely than RNA or DNA synthesis. Phenylalanine inhibits the uptake and decreases the intracellular pool of several amino acids. Certain amino acids added in exc