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Phenylalanine blood levels and clinical outcomes in phenylketonuria: A systematic literature review and meta-analysis

✍ Scribed by Susan E. Waisbren; Kay Noel; Kyle Fahrbach; Catherine Cella; Diana Frame; Alex Dorenbaum; Harvey Levy


Book ID
116988012
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
169 KB
Volume
92
Category
Article
ISSN
1096-7192

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Although pathogenesis of phenylketonuria is not completely understood, a low phenylalanine diet is effective to prevent severe neurological impairment, mental retardation and behavioural difficulties. Treatment recommendations heavily rely on neuropsychological research; however, single study result