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Phenoxodiol, an anticancer isoflavene, induces immunomodulatory effects in vitro and in vivo

✍ Scribed by Sylvianna Georgaki; Margarita Skopeliti; Marinos Tsiatas; Katerina A. Nicolaou; Kyriaki Ioannou; Alan Husband; Aristotelis Bamias; Meletios A. Dimopoulos; Andreas I. Constantinou; Ourania E. Tsitsilonis

Book ID: 114778600
Publisher: Carol Davila University of Medicine Bucharest, Romania
Year: 2009
Tongue: English
Weight: 805 KB
Volume: 13
Category: Article
ISSN: 1582-1838
DOI: 10.1111/j.1582-4934.2009.00695.x

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## Abstract Phenoxodiol (2H‐1‐benzopyran‐7‐0,1, 3‐[4‐hydroxyphenyl], PXD) is a synthetic analogue of the naturally‐occurring plant isoflavone and anticancer agent, genistein. PXD directly induces mitotic arrest and apoptosis in most cancer cells and is currently undergoing clinical trials, as a che