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Phenotypic variability in Meckel–Gruber syndrome

✍ Scribed by T. I. Farag; R. Usha; R. Uma; S. A. Mady; K. Al-Nagdy; M. H. El-Badramany


Book ID
115090082
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
239 KB
Volume
38
Category
Article
ISSN
0009-9163

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Meckel-Gruber syndrome, also known as dysencephalia splachnocystica, was originally described by Meckel in 1822, later by Gruber, and more recently by Opitz and Howe. More than 50 cases of this severe disorder have been reported.' This syndrome is characterized by microcephaly secondary to cerebral