## Variable proportions of Hodgkin's disease (HD) cases are associated with the Epstein-Barr virus (EBV), but the role of EBV in HD is not entirely clear. Hodgkin and Reed-Sternberg (HRS) cells of EBV-associated HD are characterized by expression of the EBV gene product LMP1. In other cellular envi
PHENOTYPIC MODULATION OF HODGKIN AND REED-STERNBERG CELLS BY EPSTEIN-BARR VIRUS
β Scribed by HERBST, HERMANN; RAFF, THORSTEN; STEIN, HARALD
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 699 KB
- Volume
- 179
- Category
- Article
- ISSN
- 0022-3417
No coin nor oath required. For personal study only.
β¦ Synopsis
Expression of the Epstein-Barr virus (EBV) gene product L M P l is found in tumour cells in varying proportions of Hodgkin's disease (HD) cases. It is not clear which cellular genes are influenced by EBV in HD. A total of 387 H D cases were tested for differences among LMP1-positive and -negative cases with respect to age,
π SIMILAR VOLUMES
## Abstract Isolation of single cells permits analysis of DNA or RNA from individual cells among heterogeneous populations. This technique is particularly useful in the study of classical Hodgkin's lymphoma (cHL) due to the scarcity of H/RS tumor cells among large numbers of reactive leukocytes. In
## Abstract In the search for viruses in Hodgkin lymphoma (HL), it was reported that the measles virus (MV) can be detected in the HodgkinβReed/Sternberg (HRS) cells of a large fraction of cases from Israel by immunohistochemistry or __in situ__ hybridisation, suggesting a potential role of this vi
## RCAS1 (receptor-binding cancer antigen expressed on SiSo cells) is present in neoplastic cells, induces apoptosis of natural killer (NK)/T cells and plays a role in immune evasion. Fas ligand (FasL) is considered to have similar roles. The Epstein-Barr virus (EBV)-encoded latent membrane protein