Phenotypic instability in a tif-1 mutant of Escherichia coli
โ Scribed by Hayes, William
- Book ID
- 104729182
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 284 KB
- Volume
- 147
- Category
- Article
- ISSN
- 0026-8925
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โฆ Synopsis
Merodiploids of the type tif-1/F'tif+, constructed in E. coli K12 strain T44(lambda), show that the tif-1 mutation is recessive with respect to induction of phage lambda and thermolability. An additional manifestation of tif-1 expression is increased tolerance to low levels of streptomycin (SM) and chloramphenicol (CM) and this, too, is abolished in the merodiploids.
๐ SIMILAR VOLUMES
The mutant T44(lambda) of Escherichia coli K12, grown in the presence of adenine, develops an increased tolerance to streptomycin. In cultures grown on streptomycin, the ts character (tif) may temporarily be suppressed but, on further transfer, both the temperature-sensitive phenotype and streptomyc